230 research outputs found

    Probing the Structure of Gamma-Ray Burst Jets with Steep Decay Phase of their Early X-ray Afterglows

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    We show that the jet structure of gamma-ray bursts (GRBs) can be investigated with the tail emission of the prompt GRB. The tail emission which we consider is identified as a steep-decay component of the early X-ray afterglow observed by the X-ray Telescope onboard Swift. Using a Monte Carlo method, we derive, for the first time, the distribution of the decay index of the GRB tail emission for various jet models. The new definitions of the zero of time and the time interval of a fitting region are proposed. These definitions for fitting the light curve lead us an unique definition of the decay index, which is useful to investigate the structure of the GRB jet. We find that if the GRB jet has a core-envelope structure, the predicted distribution of the decay index of the tail has a wide scatter and has multiple peaks, which cannot be seen for the case of the uniform and the Gaussian jet. Therefore, the decay index distribution tells us the information on the jet structure. Especially, if we observe events whose decay index is less than about 2, both the uniform and the Gaussian jet models will be disfavored according to our simulation study.Comment: 21 pages, 10 figures, the paper with full resolution images is http://theo.phys.sci.hiroshima-u.ac.jp/~takami/research/achievements/papers/003_full.pd

    統合失調症治療におけるアリピプラゾールとリスペリドンの認知機能に対する影響

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    広島大学(Hiroshima University)博士(医学)Doctor of Philosophy in Medical Sciencedoctora

    Analysis of a change in bacterial community in different environments with addition of chitin or chitosan

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    The temporal changes of a bacterial community in soil with chitin or chitosan added were analyzed by PCR-denaturing gradient gel electrophoresis (DGGE) targeting the 16S rRNA gene using total DNAs prepared from the community. Band patterns of PCR-DGGE confirmed that 31 species become predominant after the addition of chitin or chitosan. The determination of the nucleotide sequences of the bands of the 31 species indicated that 20 species belonged to the division Proteobacteria, and that the genus Celivibrio was apparently predominant among them (7/20). The 16S rRNA sequences of the 16 deduced species (16/31) showed less than 98% similarities to those of previously identified bacteria, indicating that the species were derived from unidentified bacteria. The total community DNAs extracted from bacterial cells adsorbed on the surface of flakes of chitin and chitosan placed in a river, a moat, or soil were subjected to PCR-DGGE to examine the extent of diversity of chitinolytic bacteria among different environments. The predominant species significantly differed between the chitin and chitosan placed in the river and moat, but not so much between those placed in the soil. The large difference between the diversities of the three bacterial communities indicated that a wide variety of bacteria including unidentified ones are involved in the degradation of chitin and chitosan in the above-mentioned natural environments. (C) 2009, The Society for Biotechnology, Japan. All rights reserved.ArticleJOURNAL OF BIOSCIENCE AND BIOENGINEERING. 109(5):472-478 (2010)journal articl

    Enrichment of Spermatogonial Stem Cells using Side Population in Teleost

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    Spermatogenesis originates from a small population of spermatogonial stem cells; this population can maintain continuous sperm production throughout the life of fish via self-renewal and differentiation. Despite their biological importance, spermatogonial stem cells are not thoroughly characterized because they are difficult to distinguish from their progeny 5 cells that become committed to differentiation. We previously established a novel technique for germ cell transplantation to identify spermatogonial stem cells based on their colonizing activity and their ability to initiate donor-derived gametogenesis in the rainbow trout (Oncorhynchus mykiss). Although spermatogonial stem cells can be retrospectively identified after transplantation, there is currently no technique to prospectively enrich for or purify spermatogonial stem cells. Here, we describe a method for spermatogonial stem-cell enrichment using side-population. With optimized Hoechst 33342 staining conditions, we successfully identified side-population cells among type A spermatogonia. Side-population cells were transcriptomically and morphologically distinct from non-side-population cells. To functionally determine whether the transplantable spermatogonial stem cells were enriched in the side-population fraction, we compared the colonization activity of side-population cells with that of non-side-population cells. Colonization efficiency was significantly higher with side-population cells than with non-side-population cells or with total type A spermatogonia. In addition, side-population cells could produce billions of sperm in recipient. These results indicated that transplantable spermatogonial stem cells were enriched in the side-population fraction. This method will provide biological information that may advance our understanding of spermatogonial stem 20 cells in teleosts. Additionally, this technique will increase the efficiency of germ-cell transplantation used in surrogate broodstock technology

    Development of a Si/CdTe semiconductor Compton telescope

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    We are developing a Compton telescope based on high resolution Si and CdTe imaging devices in order to obtain a high sensitivity astrophysical observation in sub-MeV gamma-ray region. In this paper, recent results from the prototype Si/CdTe semiconductor Compton telescope are reported. The Compton telescope consists of a double-sided Si strip detector (DSSD) and CdTe pixel detectors, combined with low noise analog LSI, VA32TA. With this detector, we obtained Compton reconstructed images and spectra from line gamma-rays ranging from 81 keV up to 356 keV. The energy resolution is 3.8 keV and 7.9 keV at 122 keV and 356 keV, respectively, and the angular resolution is 9.9 degrees and 5.7 degrees at 122 keV and 356 keV, respectively.Comment: 12 pages, 14 figures, submitted to SPIE conference proceedings vol. 5501, "High-Energy Detectors in Astronomy", Glasgow UK, 6/21-6/24 200
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